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Comparison of Bacterial Exotoxins and Endotoxin
Exotoxin | Endotoxin |
|---|
| Produced by both Gram-positive and Gram-negative bacteria | Produced only by Gram-negative bacteria |
| Released from cell | Integral part of cell wall |
| Protein | Lipid A of lipopolysaccharide |
| Many types of exotoxin based on structure and function | Only one type of endotoxin |
| Heat labile | Heat stable |
| Specific receptors on host target cells | Diverse range of host cells and systems affected |
| Specific effects in host | Diverse range of effects in host |
| Toxoids can be made by treating with formalin | Toxoids cannot be made |
Designed & Maintained by David M. Rollins
Copyright © 2000, D.M. Rollins and S.W. Joseph
Revised: September 2003
URL: http://life.umd.edu
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